Background: The cardiac and respiratory arrest has high mortality rate which can be easily prevented with simple maneuver and skills and CPR which is an effective procedures if adopted under BLS within early critical minutes of cardiac and respiratory arrest. The aim of this study is to determine the level of awareness of basic life support (BLS) among doctors. Methods: Cross-sectional study conducted on doctors working in Liaquat University hospital Hyderabad and Jamshoro. A multi-section questionnaire regarding awareness of Basic Life Support. In total 348 doctors were selected through convenient non-probability sampling technique. Analysis was done in SPSS version 22.0 & Chi-square test was applied to seek association between variable of interest. Results: The relationship of awareness about BLS to age & gender of respondents cumulatively showed significant association (p=0.01). Regarding years of job experience, 60.91% had experience 2-6 years; another 11.8% participants had experience of more than 14 years. Regarding previous experience of BLS, 69% of respondents replied that they had previous experience of BLS. Around 94.0 respondents were of the opinion that CPR procedure should bemandatory to all health care providers. There were 71.8% respondents who had complete knowledge about all components of chest compression during CPR. Conclusions: Despite the high level of awareness about BLS among doctors & enabling environment of hospitals, there is a gap in practicing it. This gap needs to be filled through continuous persuasion of health care providers.