Background: Worldwide health systems are facing an increasing number of challenges, while governments remain dedicated to searching for cost-effective options to enhance the capacity of national health systems to perform well. Although the relationship between devolution and disparities in access to health care is mixed, most studies do not attribute observed disparities in healthcare use to Devolution. This review was performed to synthesize evidence around this issue. Specifically, the objective was to answer the question: “What are the contribution of devolution in health financing, health leadership, and health information systems?”. Methods: CrossRef, Google Scholar, Academic keys, Open Academic journals index, MEDLINE, Embase, CINAHL, and PsycINFO were searched with terms related to devolution and health. The search included terms related to health financing, health information systems, and health leadership. Findings were presented within a narrative synthesis. Quality of the evidence was evaluated using the Cochrane risk of bias tool and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Findings: A few studies, all cross-sectional studies, met the selection criteria for this review. Most studies noted the Healthcare is a major element of national budgets worldwide in as much as all levels vary across countries, systems have come under increased pressure to ensure that resources are spent efficiently.