The main purpose of this study was, to assess the factors influencing practice of patient education among nurse Sir Ganga Ram hospital Lahore. The patient teaching is considered an important aspect of quality healthcare among nursing care. Patient education is necessary for the patients as it improves the patients' satisfaction and decrease the level of anxiety and short their stay in hospital. The significance of this study was minimizing the factors and enhances the nurse's attention toward educating the patient regarding disease which improve patient health and reduce the stay of patients in hospital. A cross section study design was used to explore factors influencing the practice of patient education among nurses Sir Ganga Ram hospital Lahore. Random sampling techniques were used in selecting 171 nurses at Sir Ganga Ram hospital. Questionnaire is Adapted from prior studies [1]. Questionnaire consist on three part, one part is the demographic and second part is knowledge and practice of patient education and 3rd part is factors influencing practice of patient education. The data was analyzed using SPSS version 16.the main finding of this study according to chi square knowledge and practice of patient of education and workload, work experience, culture barrier, lack of time, insufficient staff, are the key factors that influencing practice of patient education among nurses.