Background: A number of studies conducted in different parts of India on HIV/AIDS awareness revealed widespread ignorance and misconceptions about this deadly disease among young people. Methods: This cross sectional was conducted among BSc Nursing students in Shimla city. A purposive sampling technique was used to select the BSc nursing college and 25 nursing students from each study year (1st to 4th) were included. Information regarding their knowledge, regarding HIV/AIDS was obtained using a self-administered, pre-tested, semi-structured questionnaire. Data was analyzed using Epi info v7 software using appropriate statistical tests. Results: Mean age of the participated 100 BSc. Nursing students was 20.26 ± 2.360 years. 13% BSc. Nursing students having very good knowledge, 67% having good knowledge, 19 % had fair knowledge and 1% have poor knowledge about cause, mode of spread, prevention, control and treatment of HIV/AIDS. A statistically significant difference was found among the mean knowledge score between different study years of nursing students. Conclusions: These findings indicate that there is need to further increase the knowledge regarding HIV/AIDS which can be increased by structured teaching programmes and awareness workshops for the nursing students.