Pressure ulcers are the major problem of bed case patients in all the hospitals. There are great chances to develop pressure ulcers in those patients who are in critical condition and admitted in the hospital for a long time. Due to prolonged stay in the hospital and negligence of health care provider pressure ulcers can be developed. Prevention is better than cure because if once pressure ulcer developed it is difficult to treat. So nurses should take precautionary measure to prevent from pressure ulcers. This study mainly focuses on knowledge and practice of nurses regarding pressure ulcers prevention if nurses have accurate knowledge regarding prevention of pressure ulcers they can manage it timely before its development .Pressure ulcers can be prevented by regular assessment while providing nursing care to the patients Maggi, 2010. The absence of pressure ulcers in bed ridden patients is generally known as measure of quality nursing care and performance of practice of nurses. Assessment of Knowledge & Practice among nurses regarding prevention of Pressure Ulcer in Mayo Hospital Lahore”.