The present study aimed to evaluate the effect of educational program on quality of life among elderly regarding oral health. A quasi-experimental pre-test-andpost-test design was utilized to conduct this study. The study was conducted in the geriatric social club in Zagazig City. A purposive sample of 75 elderly subjects who fulfilled the study inclusion criteria. Five tools were used in the present study; Tool I was a structured interview questionnaire to assess elderly’s demographic characteristics, medical history, oral health status, periodic examination of the mouth, dietary habits, and smoking habits, Tool II was elderly oral health knowledge structured interview questionnaire, Tool III was elderly oral self-care practices questionnaire and checklist, Tool IV was the Oral Health Assessment Tool (OHAT) For Non –Dental Professional, and Tool V was Oral Health Impact Profile (OHIP-14) Short Version. The results revealed post-program statistically significant improvements in OHRQoL scores, oral health knowledge, oral self-care practices, and oral health assessment (p<0.001). The follow-up phase showed some declines, but still significantly higher compared with the pre- program levels (p<0.01). The educational program is effective in improving the elderly’s oral health related quality of life.