Globally there is an alarming situation where incidences of burn injury are very high. Every year approximately 265000 deaths are reported globally due to fire and burn related injuries and low income countries are affected the most. Worldwide statistics are such that in south East Asia (57%) deaths are reported due to burn injury, followed by Africa about 12%. The rate is lower in Eastern Mediterranean region which is about 11%. The main purpose of this study was, to assess the nurse’s practices related to aseptic techniques in management of burn patients at Jinnah Hospital and Mayo Hospital Lahore. A cross sectional descriptive survey was performed. A convenient sample of n=75 was used to collect the information. A structured questionnaire with demographic variables and causes variables was applied. The data was analyzed on SPSS version 21. 60% said that there appropriate adequate sink-be available, 92% said that there is water and soap supply in the ward while 98.7% said that there are adequate surface disinfectant, 52% said that adequate shoe cover before procedure and 98.67% answers are adequate nurse preparation before procedure. The purpose of this study was to assess the nurses practices related to aseptic techniques in burn patients, where very satisfactory practices were found.