The latest threat to global health is the ongoing outbreak of the respiratory disease that was recently given the name Coronavirus Disease 2019 (COVID-19). COVID-19 was recognized in December 2019, caused by a novel coronavirus which is structurally related to the virus that causes severe acute respiratory syndrome (SARS). As in two preceding instances of emergence of coronavirus disease in the past 18 years - SARS and Middle East respiratory syndrome (MERS), the COVID-19 outbreak has posed critical challenges for the public health, research, and medical communities. The goal of an infection control program is to provide a safe working environment for dental health care personnel and their patients. It is crucial for all dental practitioners to be up to date on current Centers for Disease Control and Prevention (CDC) and other important guidelines, equipments, and techniques for proper infection control. Continuous evaluation of infection control practices is important, this ensures the patients and enables the dental healthcare providers confidence that oral health care can be delivered and received in a safe and effective manner.