The field of endodontics and the success of endodontic procedures both heavily rely on effective chemo-mechanical debridement and disinfection of the contaminated root canal system. While the mechanical debridement involves removal of tissue/debris and enlargement of the canal with endodontic instrumentation (files), the chemical debridement relies heavily on irrigants and intra-canal medicaments. Current endodontic irrigation and intra-canal medications (such as 5.25% sodium hypochlorite and calcium hydroxide) used in endodontics do not provide adequate and complete bacterial eradication during endodontic treatment. It has been suggested that both sodium hypochlorite and calcium hydroxide are irritating and cytotoxic to dental and periodontal tissues if these materials reach beyond the confines of pulp canal space. A new material and method for disinfection is desirable.