Saudi Journal of Biomedical Research (SJBR)
Volume-4 | Issue-02 | 73-80
Original Research Article
The Effect of Hydro- Extract of the Seed of Lycopersicion esculentum (Tomato) on Wound Healing Using Wistar Rats
Edibamode Ezon-Ebidor Innocent, Osiya Deborah Abosede, Paul John Nwolim
Published : Feb. 28, 2019
Abstract
Background: The word “wound” is as old as man’s creation. Wound can be defined as an injury to the body in which the
skin, tissue or organ is broken by some external force such as a blow or surgical incision, with damage to the underlying
tissue. AIM: This study was aimed at evaluating Wound Morphometry with respect to wound size and rate of wound
contraction using tomatoe seed. Materials and Methods: The Solanum lycopersicum seeds were prepared using 28.0g of
blended S. lycopersicum seeds after drying. 24 male wistar rats separated into two groups; experimental and control (of
12 each) was used in this research. A wound size of 2cm by 2cm which exposed the panniculus adiposus was inflicted on
the right dorso-lateral shaved aspect of the thorax after anaesthetizing. The wound sizes were immediately measured
using a 4cm by 4cm template of transparent sheet and placed on a graph sheet for counting of the small blocks. The
experimental group were administered the seed extract while control group was merely dressed without seed extract.
Results and Disccusion: The rats treated with L. esculentum (experimental) had a mean wound healing (closure) day of
15.75 ± 1.49 while those treated without seed extract had a mean wound healing (closure) day of 19.50 ± 1.73.
Conclusion: The seed of Cherry tomato (Lycopersicon Esculentum) was concluded to have accelerating contracting/
healing (closure) effect with respect to the statistical significant mean value on wound healing (closure) day.