Aims: To evaluate the management of patients initially refusing care and their treatment under conscious sedation by the inhalation of Equimolar Mixture of Oxygen-Nitrous Oxide in the Department of Paediatric Dentistry at the Faculty of dental medicine in Monastir. Settings and Design: A 5 years retrospective study. Methods and Material: Dental session’s treatment under conscious sedation were done once a week. Data for only one operator was collected. Data entry was performed using SPSS statistical software. Quantitative variables were expressed by their mean and standard deviation and categorical variables by their number and frequency. Differences with P-value < 0.05 were recorded as statistically significant. Results: The sample represents 161 patients (226 care sessions), the majority of patients treated under conscious sedation are aged between 3 and 30 years. The mean age is 8.02 years with a standard deviation of 4.591 years. The most represented age group is that of 5-14 years with 74% of the total number. The category of the most treated patients in our study were disabled patients with 49%, then young children with 36% and anxious patients with 13%. The category of occasional indications related to the act represents only 3%. Recruitment was mostly performed within the Department of Paediatric Dentistry. Extractions represent 40%, no serious side-effects were observed. The success rate was 93.2%. Conclusions: Since it is carried out in a Paediatric Dentistry department, this study provides a vision of conscious sedation benefits with young patients requiring this specific treatment.