Hypertension can be defined as a condition in which the force of blood against the artery walls is too high. This study was planned to analyses cost variations of anti-hypertensive drugs available in Indian market. There is a wide range of variations as the price of drug marketing in India. This study was conducted by taking the maximum and minimum cost of anti- hypertensive agents manufactured by different brands of same drug, strength and dosage forms. The data is obtained from the current index of medical specialties [CIMS] April-July 2018. The cost ratio and percentage cost variations were calculated for each anti-hypertensive drug. The average percentage price variation of different brands of the same oral anti-hypertensive drugs in Indian market is very wide.