Facial trauma, with or without life- and sight-threatening complications, may arise following isolated injury, or it may be associated with significant injuries elsewhere. Trauma management has evolved significantly in the past few decades thereby reducing mortality in the golden hour. However, challenges remain, and one such area is maxillofacial injuries in a polytrauma patient. A systematic review of the literature was undertaken to formulate an evidence-based approach to the treatment of life-threatening maxillofacial trauma. This review article aims to provide a concise, contemporary guide for the knowledge about complications and treatment of maxillofacial trauma in the emergency setting.