Background: This study was designed to get insight on how the knowledge, attitude and perception of anatomy students across various divisions in the department of Anatomy, University of Port Harcourt. Important information was mapped out during this study and this knowledge is capable of transforming the undergraduate anatomy curriculum across Nigeria to position the students in their career and the overall development of anatomical sciences. If we want to gain a better understanding of teaching and learning in anatomy, it may be pertinent to move beyond the question of how and consider also the what, why and when of anatomy education. Aim & Objectives: This study was aimed at investigating the Knowledge, Attitude and Perception of the Divisions of Anatomy among University of Port Harcourt Anatomy Students, Nigeria. Materials & Methods: A purposive sample of 420 anatomy students from the 1st, 2nd, 3rd, and 4th year participated in the study. Each class came together during their semester examination and a mentorship form was issued to them to indicate the aspect of anatomy they are interested in. Data were analyzed and recorded. Results and Discussions: The result of the study indicated that clinical anatomy had a higher percentage of 21.65%, reproductive biology (18.47%), cell and tissue biology (9.87%), neurobiology (10.51%), physical and forensic anthropology (13.38%), and radiologic anatomy (9.87%) while multiple selections with 21.65%. The first year students showed more interest in Clinical Anatomy with a modal frequency percentage of 38.16% while the least percentage frequency was found in third year class with 9.38%. Conclusion: It is glaring that we are entering a time of paradigm shift aided by new understandings and new technologies as in all such times, views are held strongly and expressed emotionally. The University of Port Harcourt has taken the bold step restructure her curriculum for Anatomy education to flow with the current tide in meeting specific needs by diversifying Anatomy into divisions such as clinical anatomy, cell and tissue biology, reproductive biology, radiologic anatomy, neuroscience, physical and forensic anthropology.