Comparative evaluation of wettability of 3 different root canal sealers on dentin. 30 dentin blocks were prepared from single rooted maxillary anterior teeth. After storage and adequate cleaning protocol, they were surface treated with 17% EDTA (Glyde File Prep, Dentsply Maillefer, Ballaigues, Switzerland) Prime Dental Products) for 5 minutes. Following this, they were divided into 3 groups (n=10) for: Group I: AH Plus, Group II: Endo Sequence BC Sealer, Group III: MTA Fillapex. Controlled volume of each sealer was placed onto the dentin blocks using a customized wire loop. The contact angle in each case was measured using Dataphysics OCA Easydrop software on a dynamic contact angle analyzer for 1 minute. Readings will be analysed with suitable statistical tests. The contact angle values for AH Plus sealer were significantly lower when compared to the other two sealer groups. The wettability of AH Plus sealer on the root surface dentin was found to be better than Endosequence BC Sealer and Endoseal MTA.