Prior to initiation of endodontic treatment possibility of extra roots and canals should be considered. The incidence of three canals in mandibular second premolar has been found to be between 0.46-0.5%. The present series describes nonsurgical endodontic treatment of a mandibular second premolar having three canals and three roots and a mandibular first premolar having two roots and three canals. In the first case, three orifices were located and in the second case a single orifice which bifurcated into two canals in the coronal portion and then one canal further divided into two and three canals exited from the apex was seen. With good operator skill and knowledge of root canal anatomies, teeth with extremely complex root canal morphologies can have successful treatment outcome even if treated non-surgically.