Saudi Journal of Oral and Dental Research (SJODR)
Volume-3 | Issue-10 | 319-322
Original Research Article
Evaluation of Clinical Effect of Oral Vitamin D3 Supplementation in the Treatment of Chronic Periodontitis with Type 2 Diabetes Mellitus-A Randomized Controlled Trial
Dr. G. Ramaprabha, Dr. S. Senthil kumar, Dr. John William Felix, Dr S. Lakshmisree, Dr Srinivasan
Published : Oct. 30, 2018
Abstract
To assess the clinical outcome of oral Vitamin D3 Supplementation in Type
2 Diabetes Mellitus patients with generalised chronic adult Periodontitis. A total of 92
subjects, comprising 46 in non diabetic and 46 in diabetic group were enrolled in the
clinical trial according to the inclusion and exclusion criteria. Periodontal clinical
parameter, Probing Pocket Depth (PPD) was assessed at baseline. Following initial
examination Scaling and root planing was completed for all the subjects enrolled in the
study and by cluster randomization first 25 subject subjects from each group were
supplemented with oral vitamin D3 granules of 60,000IU once a week for 8 weeks
following SRP. At the end of the study after 8 weeks, Probing Pocket Depth was
reassessed. Significant improvement was seen in both interventions namely SRP
+VITAMIN D and SRP alone .But marked reduction in PPD was seen in SRP+vitamin
D supplemented group. Reduction in PPD was more for Non diabetic subjects when
compared to Diabetic subjects. Vitamin D supplementation can be used as an adjunct to
SRP for both diabetic and non diabetic patients with chronic periodontitis in vitamin D
deficient subjects.