Calcification in the carotid artery (CACs) can be visible in the panoramic radiographs (PRs) near the region of the cervical vertebrae C3-C4, posterior to angle of mandible. The aim of this study was to evaluate the incidence of CACs on PRs and their linkage with hypertension, age, gender and smoking habits. PRs of 2000 patients were evaluated. The age group was chosen between 20 to70 year old people and their PRs had been taken for different clinical reasons. Information about smoking habits, hypertension and other vascular events was obtained from OPD case papers. The observers analyzed the presence of radiopaque mass in the region of posterior to angle of mandible bilaterally on PRs. The results showed a 0.6 % incidence of CACs on 2000 PRs. In our study no significant relationship was found between smokers and incidence of carotid artery calcification .In our study significant statistical correlation found between CVD and PAD and associated risk factor with CAC on panoramic radiographs.