Ameloblastoma is the most frequent odontogenic tumor ascending from dental epithelium, and is branded by its histological resemblance to the enamel organ of the developing tooth germ. Although defined as a benign neoplasm, ameloblastomas are locally disparaging and a high recurrence rate is observed if the lesions are not entirely expurgated. Management should be built on precise clinical details, radiographs, special imaging and a illustrative biopsy, followed and reviewed by an oral pathologist and a maxillofacial surgeon. Each case is distinctive and has to be considered in the clinical context and the relationship of the lesion to its surrounding tissues, histological type, and recurrence rate. The present article is a review of the existing literature concerning management of ameloblastoma.