Successful management of furcation involved (FI) teeth is still a challenge for clinicians. Multirooted teeth are at higher risk of periodontal destruction and early tooth loss due to their complex anatomy and posterior location in the arch. Maintenance of oral hygiene around furcation involved regions is difficult, resulting in early, rapid and severe periodontal destruction. The outcomes of conservative and regenerative therapies are unpredictable in such teeth. Resective periodontal therapy in combination with endodontic and prosthetic treatments, offers a more practical and predictable approach in management of such advanced FI teeth. This multidisciplinary approach not only treats and preserves the tooth along with its periodontium in part, but also restores its function as a whole. This case series presents bicuspidization, hemisection and root resection as resective periodontal therapy in the predictable and successful management of advanced grade II, grade III and grade IV FI teeth.