Peripheral giant cell granuloma (PGCG) is a non-neoplastic, tumor-like reactive lesion occurring exclusively on gingiva/alveolar crest. It is also known as giant cell epulis, osteoclastoma, giant cell reparative granuloma or giant cell hyperplasia. Clinically, it appear as pyogenic granuloma, peripheral ossifying fibroma and many other peripheral lesions seen in the oral cavity, thereby histopathology is mandatory for the diagnosis of this lesion. This article reports a peripheral giant cell granuloma arising at mandibular anterior region in a 50 years old male patient. The biopsy specimen revealed features consistent with PGCG.