The world of implant ology is continuously expanding. The application of computer-aided design and computer-aided manufacturing (CAD/CAM) to advanced dental rehabilitation programs is one of the most interesting innovations in this area. In fact, this technique offers high precision and simpler fabrication protocol. This paper describe three cases of advanced dental rehabilitation carried out using CAD-CAM technology associated with immediate functional loading protocols for reducing to the minimum the surgical times. Extremely positive results were evidenced in our patients. Aesthetic and functional outcomes, as well as prostheses stability, were satisfactory. The main aim of the present report is to show the brilliant outcomes that we obtained with the use of this procedure. We highlight that this method may guarantees numerous advantages such as shorter treatment time, elimination of human error in the manufacturing process and positive aesthetic and functional outcomes. Furthermore, it facilitates the performance of surgery.