Change is inevitable. If any change occurs during any event whether it’s natural or man – made causes stress unless the change is accompanied by some benefits. In the present periods of COVID – 19 outbreaks various changes have been brought into the organizations in particular and among the people in general as per the norms of World Health Organization (WHO). Hence, the present piece of research endeavor is an effort to find out the predictors of organizational change with particular reference to doctors working in Darbhanga Medical College and Hospital (DMCH). For the present study total sample only sixty (N=60) doctors were selected randomly from Darbhanga Medical College and Hospital (DMCH) by contacting on mobile, WhatsApp and Google mail. Total Subjects’ age ranged between 28 to 52 years. Data were collected through questionnaire schedules. After collecting the data on the items of the schedules, individual scores were obtained for giving statistical treatment using SPSS (Statistical Package for the Social Sciences) through computer to find out the predictors influencing organizational change during COVID –19 outbreaks. Having analyzed the data only three dimensions of occupational stress, viz., ‘role overload’, ‘responsibility for persons’, and ‘strenuous working conditions’ have been found as the predictors of organizational change, although, doctors group, undertaken for the present study, working in DMCH have been found to have positive reactions towards change. Finally, obtained results have been discussed in detail by highlighting the exigency of situations prevailing throughout the nations of the world.