This study aims to find out the relationship between self-disclosure and interpersonal communication of MTs Lab IKIP Al Washliyah students. The research design used descriptive correlational with quantitative methods. Data collection techniques used a questionnaire. The questionnaires were self-disclosure questionnaire and interpersonal communication questionnaire. The self-disclosure questionnaire amount 34 statements and the interpersonal communication questionnaire amount 35 statements which were previously tested and analyzed to obtain validity and reliability. Based on the results of research in MTs Lab IKIP Al Washliyah Medan using the calculation of product moment correlation of the two variables of self-disclosure (X) and interpersonal communication (Y) that robserved 0,435> rtable 0,284. Then it is revealed that there is a significant relationship between self-disclosure and student interpersonal communication.