Colon cancer is currently the third most common cancer in both men and women after lung and breast cancer. Incidence and mortality rates have been declining since the 1980's, partially due to improvements in screening and prevention. Colon cancer is the cancer that formed in the tissues of the colon (the longest part of large intestine). Most colon cancers are adenocarcinomas. Many studies have been done to elucidate the ability of iron to rule out colon cancer. Some of these studies encouraged using iron status as early predictors of gastrointestinal tumors. The aim of this study was to estimate level of serum iron and ferritin among colonic cancer patients according to gender, age, Hb and weigh levels. This study included 100 patients diagnosed as a colonic cancer. The majority of patients were male, 67 representing 67 % of respondents and only 33 were female representing 33%. Age distribution among patients demonstrates a majority of the age interval (40-60) years representing 46 %. The association between serum iron and ferritin was found to be significant with the level of Hb. In the distribution of study population according to weight, the majority was shown in weight between (51-70) kg representing 57 % of total respondents. Regarding correlation between serum iron, ferritin and weigh, no significant was found to be observed.