The article established the relationship between youth livelihood program fund and unemployment reduction in relation to gender in western division, Kabarole District. The study adopted an observational, cross-sectional exploration design with both quantitative and qualitative as paradigms in order to describe the data and its characteristics. Questionnaires, interview guides and focused groups discussions were employed to garner information from the respondents. Data was analyzed using frequencies, percentages and bar graphs. The study findings showed that there was a positive correlation between youth livelihood program fund and unemployment reduction in relation to gender. The study findings recommended that training of the youth groups should be handled on a case by case basis depending on the nature of the enterprises specialized in while considering the group dynamics. There should be regular follow up by the relevant offices to save the situation before it runs out of hand, increase the operational (monitoring) funds for the projects across the board. There is need to ensure capacity building of both men and women to improve their financial management and entrepreneurship skills, give males and females equal opportunities and treat them equally and have equal and easy access to the funds, the study also suggested that both males and females should be involved in policy making processes of their own groups so as to feel a sense of belongingness of their own projects.