This study investigated the effect of long hour shift on hospital nurses’, increase risk of committing errors, patients’ outcomes and satisfaction. A descriptive research design was utilized in this study to investigate the effect of long hour shift on female hospital nurses’ and patients’ care outcome and satisfaction Questionnaire was systematically distributed to nurses in each of the twenty eight wards and units of the University of Maiduguri Teaching Hospital. One hundred and ninety four respondents returned the questionnaire. The study revealed that long hour shift affects the nurses’ wellbeing and the care they provide to their patients. The study also revealed that it affects their social life. This study therefore recommends eight to ten hour shift to reduce the burden on the nurses so as to provide positive patient care outcomes.