This paper explored the influence of selected factors on the marketability of counterfeit and pirated products in Dar-es-salaam region using factorial analysis. The paper followed claims of an upsurge of counterfeit and pirated products in markets and the potential of resulting negative impacts on the health of individuals and overall economic development. A cross-sectional research design and structured questionnaires were used to collect information. The results suggest that factors like the level of income, education (awareness), price and government policies are the key drivers for the purchase of counterfeit and pirated products in Dar-es-salaam region. The study recommends of strengthening the enforcement mechanisms of the existing laws and regulations which deal with discouraging substandard products and unfair practices in markets, putting in place deliberate measures to increase public awareness of the consequences and effects ensuing from the use of counterfeit and pirated products, addressing shortfalls in the intellectual property rights protection laws and regulations and increasing surveillance by the police, inspectors and customs in informal border routes to minimize the problem.