Despite their well-known harmfulness to human health, pesticides persist largely used for plant cultivation. These molecules are highly resistant to degradation by plant metabolism, while their presence, even as traces is dangerous at phytosanitary quality and environment impact. Now, due to regulations and quality standards, food industries seek to control these contamination risks and conduct research on technologies able to efficiently eliminate pesticide residue traces. Since the mechanisms of eradicating molecules are classified in three ways of evaporation, dissolution, and thermal degradation; the decontamination process should depend on three important factors: i/ the nature of the products (composition and technological/structural aptitude), ii/ the nature of the pesticides (volatility, solubility, and thermal stability), and iii/ the type of the disinfection process. The instant treatment operations have the particularity of 1/ weak thermal degradation because of HTST (high-temperature/short-time) nature; 2/ frail solubilizing by using the steam instead of liquid soaking as heating fluid, and 3/ favorable elimination of vapor molecules through the instant autovaporization. Therefore, the present study aims at the application of the multi-flash autovaporization MFA technology in the treatment of tetrachloro-m-xylene, aldrin, γ-chlordane and dieldrin pesticide residues in the case of rapeseed oil (brute). This resulted in drop-down levels of 45.2%; 30.6%; 32.2%; and 29.2%, respectively for the initial concentrations of 5, 4.51, 1.98 and 3.98 (10-2 mg/kg of oil), respectively. Far from a real optimization of the operation, 51-cycle MFA at a heating temperature of 50 °C reduced the total pesticide concentration from 15.39 to 9.99 (10-2 mg/kg oil) .