Indonesia's chemical industry is faced with the challenge of increasing its supply chain competitiveness, while the chemical industry in Indonesia generally still does not have a holistic performance measurement system in its supply chain. The objective of this research is to develop the framework of supply chain performance measurement of the chemical industry using SCOR and DMAIC models. The research stages are the selection of chemical industry supply chain indicators, benchmarking of indicators, development of the framework for supply chain performance measurement for Indonesia’s chemical industry, and the improvement of the supply chain performance. The implementation was carried out at the cases in the market leader company which produces textile dyes product in Indonesia. The result of expert consensus recommends 28 indicators of the industrial chemical supply chain. The best in class for each supply chain performance indicator become the performance target on the performance measurement framework which is developed. The results of measuring the performance of the chemical industry supply chain in the textile dyes product showed good performance at flexibility aspect, medium at cost, reliability, and asset management cost aspect, and low at responsiveness aspect. There were three critical to quality (CTQ) for responsiveness aspects; these are demand analysis, raw material issue, and breakdown machine. The recommended improvements are to provide training on demand analysis, to improve communication with the regional party, to provide alternative vendors, raw material scheduling, procurement of buffer stock for raw material critical, and scheduling preventive maintenance.