A comparative analysis of head-loss equations under EPANET computer program and Hardy Cross iterative method was carried out in this project. A single period analysis was performed on a three-loop network in EPANET’s work space. Also, the network was solved with the Hardy Cross method, applying a single loop adjustment algorithm. The frictional head-losses in each of the methods were computed using the Darcy Weisbach and Hazen Williams headloss equations. The convergence of the flow rate corrections in each of the cases was evaluated and compared. Results of the analysis showed that the flow rate corrections converged at the 4th and 14th iteration for the two head-loss formulae in EPANET and Hardy Cross method respectively. The results were subjected to t-test on 5% level of significance, and it showed that there is no significant difference in the use of either of the head-loss equations for computations in each of the methods. Thus, any one of the head-loss equations can be used for effective analysis of pipe networks.