As per the ayurvedic text vayu (vata) is the main governing factor in our body as well as in the universe. Also it is mentioned that the three Doshas are predominant in different stages of our age like Kapha in Balyavastha (Childhood), Pitta in yuvavastha (Young age), Vata in Vriddhavastha (old age). That’s why the degeneration process is more in old age due to the predominance of Vata Dosha in our body. Sandhivata (Osteoarthitis) is one of the common examples of the degenerative disease in old age. In India Sandhivata is more prevalent in postmenopausal age group. For the management of sandhivata vatashamak drugs, Brimhan drug, snehan-swedan and Vasti chikitsa etc are being adopted as per the condition of the disease and the patient. In the present study an effort has been made to manage Sandhivata (Osteoarthritis) with matrabasti and shaman drugs. For the study total 100 no of patients of sandhivata were taken and treated with matrabasti with Sudhabala taila and ketakyadi taila. After treatment significant relief was noticed in both of the groups. In group A(Sudhabala taila) patients 14%, 66%, 16% of patients experienced complete remission, marked improvement and moderate improvement respectively. Where as in group B (Katakyadi taila) patients the same was 10%, 68%, and 20% respectively. The rest 4% in group A and 2% in group B patients were experienced no relief. Hence the group B patients showed better result in comparision to group A patients. From the study it can be concluded the matrabasti has a great scope in the management of Janusandhigata vata.