Avipattikar Churna is used in clinical practice in dealing with the case of gastric disorders since the 19th century. Amlapitta is one of the chief disorders of Gastro-intestinal tract. Colloquial term for Amla-pitta is Hyperacidity. Though various scientific researches were performed by varies Ayurvedic researchers, data of their outcome are not compiled to completely understand the pharmacology. This formulation promptly relives from major symptoms like Amlokalesh, Shirovedna, Ura-Pradesh Daha, Aruchi, Amlodgara. Neither, any complication(s)/Side effect(s) were reported so far, nor it produces addiction. 20 times of its normal dose (500mg/Kg body wt.) does not produce any acute toxicity in rats. Maximum numbers of constituents of it have Anti-ulcerogenic and Anti-oxidant property. It is an inference from all clinical study that 21- 45 days period is required to show marked improvement in the disease. Allopathic medicine uses to treat hyperacidity share a good portion of the drug market. Due to its higher safety and efficacy, it may be a good substitute for acid-lowering drugs of today.