Avocado seeds (Persea americana Mill.) have been recommended in traditional medicine which has therapeutic effects for hyperlipidemia, hypertension, and hypercholesterolemia. This study aims to analyze qualitatively and quantitatively the chemical compounds contained in hexane, acetone, ethanol and water extract from avocado seeds. The results obtained from the qualitative test showed that avocado seed hexane extract contained fatty acids. Avocado seeds acetone extract contains fatty acids, phenols, tannins, and flavonoids. Ethanol extracts of avocado seeds contain phenols, tannins, flavonoids, and alkaloids. Avocado seed water extract contains carbohydrates, phenols, and tannins. Quantitative tests of alkaloids are determined by the gravimetric method, as well as the ultraviolet spectrophotometer method for flavonoids, phenols, and tannins. The results obtained from the quantitative test showed the total alkaloid content of ethanol extract was 0.435 %, the total flavonoid levels of acetone and ethanol extract were 0.1068 % and 0.1084 % respectively, the total phenol content of acetone, ethanol and water extracts were 0.0476 %, 0.0309 %, and 0.0494 % respectively. The total tannin content of acetone, ethanol and water extracts were 0.1989 %, 0.2044 %, and 0.1804 % respectively.