Every year 3 million cases of pesticide poisoning are estimated by World Health Organization. Acute poisoning is common and urgent medical problem is in both developed and developing countries all over the world. The aim of this study was to determine the relationship of age, sex and marital status of victims in case of death due to Organophosphorus poisoning. This retrospective study was conducted in Rajshahi medical college during from January 2012 - December 2014. A total of 1290 medico legal post mortems were performed during this study period, out of which 359(27.83%) were deaths due to Organophosphorus poisoning. The majority of the victim were females 232(64.62%) while males were 127(35.37%) in number. According to age group the maximum incidence of poisoning was found in 21- 30 years 41.50% gradually decreases and minimum were observed in age group ≥61 years. Acute poisoning was observed more in married group (77.56%) than unmarried group (22.44%). Pattern of various types of poison taken varies from country to country even society to society. So we should take preventive methods that may reduce mortality and morbidity due to Organophosphorus poisoning.