The paper describes the integration of Calvinism with the development of Switzerland. The work will be with the general spatial traffic, historical and linguistic features of the Swiss Confederation, to show the development of Calvinism and Protestantism in Switzerland. Swiss reformist movement took the final victory in 1541, and with the agreement of Zurich Calvinism is accepted throughout the protestant Switzerland. Many Swiss believe that today’s wealth of the Swiss credited exactly Calvin's doctrine. Reducing life as a means of justification to God, which is strongly promoted by the Catholic Church, is not only completely worthless, but also very selfish and harmful as it leaves the duties of this world. For its part, the marvelous work promoted by Calvin's doctrine seems to be the external expression of love toward the neighbor and loyalty to the homeland, but to God. The paper will also show the data of the average GDP per capita in Swiss cantons and compare them with the religious composition from 2013, with the assumption that because of the work ethic Protestants are those cantons in which the leading Protestant population will be better off than those in which leads Roman-Catholic religion.