Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction affecting mainly young women, on this poster reporting a clinical case of a parturient parturient of 21 years old, primiparous, diagnosed myasthenia for 6 years, thymectomized, under corticosteroid therapy, azathioprine and mytelase, who presents for a pregnancy of 36 SA + 3 without signs of muscle weakness. The delivery was carried out vaginally under epidural analgesic giving birth to a newborn of 2kg800, male, Apgar a 4/4/4, lethargic with congenital myasthenia who died after 10 hours of life. The diaper suites were simple at day 4 of the postpartum the parturient presented a serious myasthenic crisis at the paraclinical exploration the biological assessment showed a slight inflammatory syndrome the therapeutic approach consisted in a conditioning of the patient, corticosteroid, prostigmine, azathioprine, mytelase, as well as a cure of 5 days of immunoglobulin. The evolution was favorable at the end of the 3rd day and the patient was transferred to the neurology department on the 6th day and left home at the end of the 10th day.