The purpose of this study was to determine the effect of: (1) the level of parental education on student achievement, (2) learning style on student achievement, (3) interest in learning towards student learning achievement, (4) learning style on student learning interest, and (5) student learning styles towards student achievement in science subjects through student learning interest in SMP Negeri 1 Martapura Timur. This type of research is included in the quantitative approach with descriptive methods. The population in this study were all students in SMP Negeri 1 Martapura Timur, totaling 157 people. The sample was determined using the Slovin formula, so as many as 143 people were obtained. The distribution of the number of samples of each grade level is determined by proportional random sampling. Data collection techniques used are using a questionnaire that has been tested for validity using Pearson Product Moment correlation and reliability using the split half method. The data obtained were analyzed descriptively and path analysis, after testing the classical assumptions namely normality, homogeneity, multicollinearity, and autocorrelation. The results of this study indicate that there is an influence: (1) the level of parental education on student achievement, (2) learning style on student achievement, (3) interest in learning towards student learning achievement, (4) learning style on student learning interest, and (5) student learning styles towards student achievement in science subjects through student learning interest in SMP Negeri 1 Martapura Timur.