The study objective was to establish Relationship between Provision of Classroom Teaching Resources and teachers’ performance of instructional roles in secondary schools in Nandi East Sub-County, Kenya. The study adopted correlational research design. Data collection tool was teachers’ questionnaire. Reliability of the instrument was tested using test re-test method. It was validated by experts. The target population was secondary school teachers while the accessible population was the 192 teachers teaching in the 30 secondary schools in Nandi East Sub-County. The study used proportionate sampling to categorize respondents into female and male teachers, boarding and day schools. Proportionate sampling was used to apportion respondents from various schools. Simple random sampling technique was used to sample the actual respondents. The Sample size was 127 teachers in the 30 sampled schools determined by using Krejcie and Morgan table of Sample size determination. The study established that there was a positive and a statistically significant relationship between provision of classroom teaching resources and performance of instructional roles. It was concluded that teachers in most of the schools were ineffective in preparing curriculum support materials, supervising students as they study, explaining concepts in class, and in using audio-visual equipment during lesson delivery. It was further established that majority of the schools had not provided ICT resources for use by teachers in performance of instructional roles. Similarly, provision of laboratory chemicals to be used during teaching of practical subjects was found to be insufficiently provided. The researcher recommends that teachers should be provided with necessary, relevant and adequate teaching and learning resources to be used during performance of instructional roles. Additionally, Teachers Service Commission (TSC) of Kenya to urgently implement Teacher Professional Development programs to address the weaknesses of teachers’ inability to explain concepts in class and encourage them to use ICT resources in teaching and evaluation.