This socio-anthropological descriptive type of study was conducted to explore the level of depression and to find out the various socio-economic, academic factors which act as barriers to study among university students of Bangladesh. The aim of this study is to estimate depression among university students of Bangladesh using statistical method. This research conducted among University students.Thesample size was 600, randomly selected from three Universities in capital city Dhaka. The depression of male students is more than female students. But it is a notable that, the female are more worried about their future carrier life than male students.