The study was conducted to assess the production and economics of mono sex male tilapia (Oreochromis niloticus) reared in nine seasonal small ponds at Patuakhali Science and Technology University research farm for a period of three months during March to May 2019.The experiment was designed in three treatments (T) each with three replications. The ponds were drained, limed and fertilized with organic and inorganic fertilizers during preparation. The stocking density was 37050 fish/ha in all three treatments. After stocking the fish ponds were fertilized weekly with cowdung, urea and TSP. Supplementary feed was not given in T1, but rice bran and mustard oilcake were given in T2 and commercial pellet feed in T3. Some water quality parameters were monitored at regular intervals and they were found within acceptable range for pond aquaculture. The survival rates were high (> 96%) in all treatments. Significantly highest production (5494.10 kg/ha in three months) was found in T3 followed by T2 (2392.23 kg/ha/3months) and T1 (1048.93 kg/ha/3 months). Similarly, significantly highest net return (Tk. 206274.64/ha with benefit cost ratio of 2.01) was found in T3 followed by T2 (Tk.33100.47/ha with benefit cost ratio of 1.24) and T1 (Tk. 8254.74/ha with benefit cost ratio of 1.11).