The present investigation was conducted to evaluate antimicrobial and analgesic activities of ethanol extract from Solanum torvum (Family: Solanaceae) aerial parts. The bioactive compounds such as glycoside, tannins, sterols, saponins, flavonoids, carbohydrates and proteins are detected in ethanol extract shown promising antibacterial activity against gram positive bacteria viz. B. subtilis and S. aureus. Analgesic activity was evaluated against both thermal and chemical induced stimuli, which were evidenced from acetic acid induced writhing, tail immersion and formalin induced paw licking test. The assessment of peripheral analgesic effect of the ethanol extracts exhibited a significant percentage inhibition in the writhings which were induced by acetic acid in mice. Similarly test drug significantly increased the latency period in the tail immersion test and the formalin study showed that both the aphasic and tonic pain was blocked by the extract. The overall analgesic effect of ethanol extract (200 and 400 mg/kg body weight, p.o.) was lower than the standard drugs aspirin. The presence of flavonoid compounds in ethanol extract of Solanum torvum aerial parts may be responsible for the analgesic effect