Ipomoea sepiaria Roxb., also known as Purple heart glory is a slender vine belonging to family Convolvulaceae. In Sanskrit it is known as lakshmana, in hindi as Bankalmi and in Malayalam as Tirutali. It is one among the ten sacred plants known collectively as “Dasapushpam” in Kerala. These plants are used for rejuvenating the body in the form of „karkidakakanji‟ in the monsoon season in Kerala which is also prescribed in text books of ayurveda. Juice of the plant is used as deobstruent, diuretic, hypotensive, uterine tonic and antidote to arsenic poisoning. The present study aims at the preliminary phytochemical screening of the successive solvent extracts of Ipomoea sepiaria Roxb. and identification of compounds in the Hexane extract by Gas Chromatography- Mass Spectrometry technique. The preliminary phytochemical screening revealed the presence flavanoids, tannins, flavanoids, terpenoids, steroids, sterols, cardiac glycosides and carbohydrates. The GC-MS analysis revealed the presence of the compounds Caryophyllene, α –Curcumene, β – Cadinene, ϒ –Elemene, Caryophyllene oxide, Asarone, Germacrone, Methyl isopimarate, Abietic acid, Lupeol, β –Amyrin and α –Amyrin which have not been so far reported in Ipomoea sepiaria. The higher percentages of compounds α- amyrin(33.341) β –Amyrin(16.28) which form the basic skeleton of triterpenoid saponins are promising.