The main objective of this study is to contribute to the knowledge of plants with antifungal and antibacterial potentials. Ethnobotanical surveys on the uses of plants cited in the traditional pharmacopoeia against vaginal infections are conducted in the markets and districts of four Cameroonian cities. The botanical data collected was recorded in the Excel 2010 version spreadsheet and processed statistically. A dendrogram showing the similarity of use of anti vaginitis plants by city and by respondents was established using the Jaccard similarity coefficient using the XlStat software. A total of 73 respondents were interviewed. The analysis of the dendrogram of similarity between the uses of plants in the four cities reveals a comparison between the knowledge of the respondents of the cities of the Center region and the dissimilarity between those of the Littoral. Thirty-four (34) plant species belonging to twenty-eight (28) plant families have been identified and the first is Asteraceae. The Guineo-Congolese phytogeographic type (12 citations) predominates. Fourteen (14) diseases and/or symptoms related to the female plant were obtained; Vaginal infections (33 citations) the first. Traditional medicines prepared are mostly preserved at room temperature (41%). Sexual intercourse comes first (37%), as a prohibition that can damage the treatment. Given the upsurge in vaginal infections in Africa, it is essential to develop a strategy to find effective means of control and especially at a lower cost to propose an alternative to conventional therapy.