Parthenium hysterophorus L. is an invasive alien species of natural and agroecosystems. It causes biodiversity loss in the former and yield loss in the later. Successful eradication of P. hysterophorus is still a distant dream. We argue that the possibilities to exploit this species for material production and services should be explored. Present study evaluates this species for phytoremediation of chromium (Cr) and nickel (Ni). P. hysterophorus plants were exposed to four concentrations of chromium (CN10, CN15, CN30 and CN40) and nickel (NN10, NN20, NN40 and NN50). The low concentrations of Cr (CN10) and Ni (NN10 and NN20) enhanced all the growth parameters studied. Shoot accumulation of Ni exceeded the root accumulation (TF<1) while TF>1 was noted for Cr. P. hysterophorus accumulates both heavy metals as evident from high biological concentration factor (BCF) and biological accumulation coefficient (BAC). Hence P. hysterophorus can act as phytoremediator of Ni and Cr.