Industrial effluent is a favourable approach for irrigation demand. But according to an estimate, the alcohol production in India has reached 2.7 million liters and the proportion of effluent is nearly 15 times of the total alcohol production. This massive quantity, approximately 40 billion liters of effluents, if disposed untreated can cause considerable stress on water sources leading to widespread damage to aquatic life. The pollution effect of distillery waste is due to high bio-chemical oxygen demand (BOD) and colour. The present study compares the effect of untreated and anaerobically treated distillery effluent on seedling growth of potato (Solanum tuberosum). It is observed that potato seedling shows less growth in different concentration (5%, 10%, 15%, respectively) of untreated effluent as compared to anaerobically treated effluent. The result of this study indicates that we should use the treated effluent for irrigation purposes.