Abstract: The purpose of this study was to find out the effect of Plyometric and weight training on selected physiological variable of football players. Total Sixty (60) male football players were selected as subject randomly who participated in the national level competition from Manipur University, Canchipur. They were divided into three equal groups and designated as experimental group (I), experimental group (II) and control group (III). Plyometric training was given to experimental group (I), Weight training was given to experimental group (II) and even though, the control group was allowed to attain their daily physical activity programme, they were not allowed to participate in the experimental treatment. The groups were administered initial tests on physiological variable. After the initial test, the Plyometric and Weight training were administered to the two experimental groups, where no special training was administered to the control group. The training was administered for the period of twelve (12) weeks, four (4) days in a week in progressive manner. To find out the significance of difference between pre and post –test means‘t’ test was employed. The level of significant was set at 0.05 levels. To find out the significance of mean difference among pre – test, post- test and adjusted means and analysis of variance techniques were employed.