Background: Preterm prelabour rupture of membranes (PPROM) is an important obstetric complication associated with maternal morbidity, prematurity and adverse neonatal outcomes. Identification of associated risk factors and assessment of pregnancy outcomes are essential for improving maternal and neonatal care. Objective: To evaluate the potential risk factors and pregnancy outcomes among women with PPROM admitted to a tertiary-level hospital. Methods: A descriptive observational study was conducted in the Department of Obstetrics & Gynaecology, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh, over six months from 27 February 2019 to 26 August 2019. Fifty pregnant women with PPROM between 28 and 36⁺⁶ weeks of gestation were enrolled consecutively and followed until delivery. Sociodemographic characteristics, obstetric history, clinical presentation, potential risk factors, mode of delivery, maternal complications and neonatal outcomes were recorded and analyzed using descriptive statistics. Results: The mean maternal age was 23.5 ± 9.54 years, and 42.0% were aged 21–25 years. Most women were multigravida (62.0%) and presented at 34–36⁺⁶ weeks (74.0%). Anaemia (28.0%), urinary tract infection (26.0%) and previous caesarean section (24.0%) were the most frequently identified potential risk factors. Caesarean section was performed in 82.0% of cases. Urogenital infection (34.0%) was the most common maternal complication. All newborns were premature, while neonatal sepsis occurred in 30.0% and birth asphyxia in 24.0%. Neonatal mortality was 8.0%. Conclusion: PPROM was associated with substantial maternal and neonatal morbidity. Early identification of associated factors, appropriate antenatal care, prompt management and adequate neonatal support are important to improve outcomes.