Objectives: This study aimed to investigate the effect of different neuromuscular training on muscular endurance of junior athletes. Methods: The experimental study enrolled 60 junior athletes’ who taking part in the school level zone athletic competitions from Sakthi Higher Secondary School, Erode Tamilnadu. The age ranged between twelve and thirteen years, which were selected to carry out the research. The subjects who met the inclusion criteria were selected using random sampling and divided into three intervention groups and a control group. The test items used to collect the muscular endurance tested by modified it ups test and performance recorded in counts. The 12 weeks of stipulated training was provided to the participants for the period of 60-minute sessions for the three alternative days in a week. Statistical Procedure: To process the results of the study, analysis of the data was done with the IBM SPSS Statistics 22 software. The statistics obtained were provided by way analysis of co variance. The level of confidence was fixed at 95% and values below p<0.05 were considered significant. Results: The one-way analysis of co variance showed a significant (p<0.05) improvement in muscular endurance over the 12 weeks of stipulated training. Conclusion: The results indicate considerable significant improvement on muscular endurance was observed. The findings indicate that the selected training regimes led to significant improvement on agility.