Introduction: Tuberculosis remains a major public health problem in Senegal and, despite effective treatment, it frequently leaves respiratory sequelae that cause chronic morbidity. This study was conducted to determine the epidemiological, diagnostic, therapeutic and evolutionary aspects of post-tuberculosis respiratory sequelae. Methodology: Retrospective and descriptive study including patients with post-tuberculosis respiratory sequelae followed at the Saint-Jean de-Dieu Hospital in Thiès (Senegal). Results: Over a period of 63 months, we identified 133 cases of post-tuberculosis respiratory sequelae. There was a male predominance (67%) with a sex ratio of 2 and an average age of 51 years. In 83% of cases, a single episode of tuberculosis was sufficient to cause respiratory sequelae. Radiological abnormalities were mainly located in the lung parenchyma (61%) and were bilateral in 86% of cases. The main types of abnormalities were fibrous condensation blocks (15.03%), followed by emphysema (14.2%), pulmonary calcifications (13.53%) and fibrosis (9.02%). The complications found mainly included aspergillosis graft (32%) and chronic pulmonary heart disease (CPC) (32%). Conclusion: Post tuberculosis pulmonary sequelae remain common in vulnerable patients, with persistent symptoms and varied lesions. The lack of targeted functional assessment calls for more comprehensive prospective studies.